Тип публикации: статья из журнала
Год издания: 2023
Идентификатор DOI: 10.20333/25000136-2023-4-37-41
Ключевые слова: ischaemia, atherosclerosis, CD38, CD31, lymphocyte, pathogenesis
Аннотация: The aim of the research. To study the interrelations between CD38, CD31 lymphocytes and development of critical ischaemia of the lower extremities. Material and methods. Th e 1st group included 75 patients with the ΙΙB degree of ischaemia and the 2nd group included 75 patients with critical ischaemia. Th e control group consisted oПоказать полностьюf 75 healthy subjects. We measured anklebone arterial blood pressure, the ankle-brachial index, toe arterial blood pressure, the transcutaneous tension of oxygen, used ultrasonic Doppler sonography and the CT-angiography. Th e CD38, CD31 level was determined using immunofl uorescence. Th e data are presented as median and quartiles - Me (LQ, UQ). Results. Th e anklebone arterial blood pressure in the 1st group did not diff er from the controls while it was 56 [34; 69] mmHg in patients with critical ischaemia. Th e toe arterial blood pressure in patients of the1st group did not diff er from the controls, and in the 2nd group, this index was signifi cantly below 41 [33; 46] mmHg. Transcutaneous tension of oxygen in the 1st group was normal, in the 2nd group it was 38 [28; 53] mmHg, ] (p2<0.001) Conclusion. High and average correlations have been found between CD31, CD38 and ischaemia, high and very high correlations were revealed between CD31 and the arterial blood flow parameters in the lower extremities, and the preserved lumen of arteries
Журнал: Сибирское медицинское обозрение
Выпуск журнала: № 4
Номера страниц: 37-41
ISSN журнала: 18199496
Место издания: Красноярск
Издатель: Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого