INDICATORS OF OXYTOCIN LEVELS IN CHILDREN WITH AUTISTIC DISORDERS AND MENTAL RETARDATION

Описание

Тип публикации: доклад, тезисы доклада, статья из сборника материалов конференций

Конференция: Scientific research of the SCO countries: synergy and integration; Beijing; Beijing

Год издания: 2023

Ключевые слова: autism spectrum disorders, intellectual disability, childhood age, behaviour, intelligence, oxytocin

Аннотация: We studied the level of oxytocin in the saliva of children with autism and mental retardation (ASD) and of children only mental retardation (MR). Data were obtained on a lower level of oxytocin in the group ASD 41.51 ± 7.29 pg/ ml compared with the group of patients MR 61.88 ± 4.8 pg/ml. At the same time, according to the results oПоказать полностьюf the correlation analysis in the main group ASD, a more significant level of dependence between the indicators of the concentration of oxytocin and autistic characteristics (rs=0.499) was established in comparison with the control group MR (rs=0.097); there was a trend towards a decrease in the severity of autistic behavioral patterns (rs=-0.003) and the concentration of oxytocin in saliva (rs=-0.045) with age in the main group ASD. Patients in the group MR showed a slight decrease in autism scores with age (rs=-0.0001) and a more marked increase in oxytocin levels (rs=-0.133). Conclusion. It is concluded that there is a significant relationship between more severe variants of autism disorders and high levels of oxytocin in children ASD. In addition, the concentration of oxytocin in the saliva of patients in this group decreases somewhat with age and little depends on the degree of intellectual impairment.

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Издание

Журнал: Scientific research of the SCO countries: synergy and integration

Выпуск журнала: Part 4

Номера страниц: 91-99

Место издания: Beijing

Издатель: Инфинити

Персоны

  • Pichugina Yulia Anatolyevna (Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University)
  • Pirogova Alexandra Viktorovna (Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University)
  • Lopatina Olga Leonidovna (Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University)

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