Тип публикации: статья из журнала
Год издания: 2011
Идентификатор DOI: 10.1007/s10517-011-1147-9
Ключевые слова: apoptosis, clasmocytosis, consecutive pregnancy, myometrium, necrosis, caspase 3, animal cell, animal tissue, article, cell count, cell death, cell density, cell structure, controlled study, cytoplasm, delivery, female, hydrolysis, involution, macrophage, mouse, multipara, muscle cell, nonhuman, parity, pregnancy, primipara, Animals, Gravidity, Immunohistochemistry, Macrophages, Mice, Mice, Inbred C57BL, Muscle Cells, Postpartum Period, Pregnancy, Animal, Time Factors, Mus
Аннотация: Elimination of "excessive" myocytes and their structures during involution of the myometrium after the first and third pregnancies was realized by clasmocytosis (eliminating the greatest volume of myocyte cytoplasm fragments), apoptosis, and necrosis (equal percentage by volume). In contrast to the first pregnancy, involution afterПоказать полностьюthe third one was not over by day 10 because of inhibited elimination of functionally lost myocytes by necrosis and apoptosis mechanisms. Presumably, this was caused by slower hydrolysis of apoptotic bodies by macrophages. The concentration of macrophages in the myometrium on day 10 of the involution period in females after the third delivery was 4-fold higher than in intact mice and in females after the first delivery during the same period. © 2011 Springer Science+Business Media, Inc.
Журнал: Bulletin of Experimental Biology and Medicine
Выпуск журнала: Vol. 150, Is. 3
Номера страниц: 378-382